discontinued

AR10665PU-N HTLV1 gp21 (351-404)

Search for all "HTLV1 gp21"

0.5 mg / €660.00

Quick Overview

HTLV1 gp21

AR10665PU-N

Product Description for HTLV1 gp21

HTLV1 gp21.
Presentation: Purified

Properties for HTLV1 gp21

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95.0% pure as determined by 10.0% SDS-PAGE (coomassie staining) and RP-HPLC.
Purification Method: HTLV-1 gp21 was purified by proprietary chromatographic technique.
Application HTLV-1 gp21 can be used as an antigen in ELISA and Western Blots.
Excellent reagent for correct detection of HTLV infections, with minimal specificity problems.
Background

Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies). 

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Description
Description:
The E.coli derived recombinant protein contains the gp21 immunodominant region, 351-404 amino acids. Fused with a GST tag at N-Terminus.
Format
Buffer System:
60mM NaCl, 50mM Tris-HCl, pH 8.0, 0.25% Sarkosil, 50% Glycerol, 10mM Glutathione
Purity:
>95.0% pure as determined by 10.0% SDS-PAGE (coomassie staining) and RP-HPLC.
Purification Method: HTLV-1 gp21 was purified by proprietary chromatographic technique.
State:
Purified
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