discontinued

AR10666PU-L HTLV1 p24 core

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1 mg / €570.00

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HTLV1 p24 core

AR10666PU-L

Product Description for HTLV1 p24 core

HTLV1 p24 core.
Presentation: Purified

Properties for HTLV1 p24 core

Product Category Proteins & Growth Factors
Quantity 1 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95.0% pure (As determined by HPLC-C4, and 10.0% PAGE). 
Purification Method: Organic extraction S-300> HPLC.
Application Antigen in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Background Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
Concentration 1.0 mg/ml
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Description
Description:
The E.coli derived recombinant protein contains the full length sequence of HTLV-I p24.
Specificity: Immunoreactive with sera of HTLV-I infected individuals.
Format
Buffer System:
50 mM NaPO4 pH 6.0, containing 1 mM DTT, and 1 mM EDTA
Purity:
>95.0% pure (As determined by HPLC-C4, and 10.0% PAGE). 
Purification Method: Organic extraction S-300> HPLC.
State:
Purified
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