discontinued

AR10666PU-S HTLV1 p24 core

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0.1 mg / €240.00

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HTLV1 p24 core

AR10666PU-S

Product Description for HTLV1 p24 core

HTLV1 p24 core.
Presentation: Purified

Properties for HTLV1 p24 core

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95.0% pure (As determined by HPLC-C4, and 10.0% PAGE). 
Purification Method: Organic extraction S-300> HPLC.
Application Antigen in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Background Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
Concentration 1.0 mg/ml
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Description
Description:
The E.coli derived recombinant protein contains the full length sequence of HTLV-I p24.
Specificity: Immunoreactive with sera of HTLV-I infected individuals.
Format
Buffer System:
50 mM NaPO4 pH 6.0, containing 1 mM DTT, and 1 mM EDTA
Purity:
>95.0% pure (As determined by HPLC-C4, and 10.0% PAGE). 
Purification Method: Organic extraction S-300> HPLC.
State:
Purified
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