AR50764PU-N IL18BP (31-194, His-tag)

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0.5 mg / €730.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

IL18BP

Product Description for IL18BP

IL18BP.
Presentation: Purified

Properties for IL18BP

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms IL-18BP, Interleukin-18-binding protein, Tadekinig-alfa
Presentation Purified
Molecular weight 20.0 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O95998
Purity > 90 % by SDS - PAGE
Background IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Shimizu,C., et al. (2012) Mod Rheumatol 22 (1), 73-79Fujita,T.,et al. (2011) Diabetes Res. Clin. Pract. 92 (3), E66-E69
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG
Molecular weight:
(187aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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