AR50032PU-S Interleukin-10 / IL10 (19-178, His-tag)

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0.1 mg / €240.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Interleukin-10 / IL10

Product Description for Interleukin-10 / IL10

Interleukin-10 / IL10.
Presentation: Purified

Properties for Interleukin-10 / IL10

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms CSIF, Cytokine synthesis inhibitory factor, IL-10, TGIF
Presentation Purified
Molecular weight 20.94 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P22301
Purity > 95 % by SDS - PAGE
Background Interleukin-10 (IL 10) is also known as human cytokine synthesis inhibitory factor (CSIF) and inhibits the synthesis of pro-inflammatory cytokines like IFN-gamma, IL2, IL3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. This protein has effects in immunoregulation and inflammation and down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Moore KW., et al. (2001). Annu. Rev.Immunol. 19: 683-765.
Mocellin S., et al. (2004). Trends Immunol. 24 (1): 36-43.

Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant IL10 protein, fused to His-tag at N-terminus, was expressed in E.coli and was purified by conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N
Molecular weight:
(181 aa), confirmed by MALDI-TOF.
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
Endotoxin level:
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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