Product Description for IRGM
Properties for IRGM
|Product Category||Proteins & Growth Factors|
|Synonyms||IFI1, IRGM1, Immunity-related GTPase family M protein, LRG-47, LRG47, MGC149263, MGC149264|
|Molecular weight||20.1 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 90 % by SDS - PAGE|
|Background||Immunity-related GTPase family M protein, also known as IRGM, is required for clearance of acute protozoan and bacterial infections. This protein functions in innate immune response probably through regulation of autophagy. It may regulate proinflammatory cytokine production and prevent endotoxemia upon infection and may also play a role in macrophages adhesion and motility.|
|Concentration||1 mg/ml (determined by Bradford assay)|
|General Readings||Singh S.B., et al. (2006) Science. 313:1438-1441Parkes M., et al. (2007) Nat. Genet. 39:830-832|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.