AR50657PU-S IRGM (23-181, His-tag)

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0.1 mg / €300.00
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Quick Overview

IRGM

Product Description for IRGM

IRGM.
Presentation: Purified

Properties for IRGM

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms IFI1, IRGM1, Immunity-related GTPase family M protein, LRG-47, LRG47, MGC149263, MGC149264
Presentation Purified
Molecular weight 20.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
F8VPC9
Purity > 90 % by SDS - PAGE
Background Immunity-related GTPase family M protein, also known as IRGM, is required for clearance of acute protozoan and bacterial infections. This protein functions in innate immune response probably through regulation of autophagy. It may regulate proinflammatory cytokine production and prevent endotoxemia upon infection and may also play a role in macrophages adhesion and motility.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Singh S.B., et al. (2006) Science. 313:1438-1441Parkes M., et al. (2007) Nat. Genet. 39:830-832
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human IRGM protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MKETLKIVSR TPVNITMAGD SGNGMSTFIS ALRNTGHEGK ASPPTELVKA TQRCASYFSS HFSNVVLWDL PGTGSATTTL ENYLMEMQFN RYDFIMVASA QFSMNHVMLA KTAEDMGKKF YIVWTKLDMD LSTGALPEVQ LLQIRENVLE NLQKERVCEY
Molecular weight:
(180aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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