Product Description for Kynurenic acid
Properties for Kynurenic acid
|Product Category||Proteins & Growth Factors|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Application||Immunohistochemistry on frozen and paraffin sections.|
|Background||Kynurenic acid is a product of the normal metabolism of amino acid L-tryptophan. It is formed from L-kynurenine, a reaction catalyzed by the enzyme kynurenine-oxoglutarate transaminase. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important neurophysiologic and neuropathologic processes. As a result, kynurenic acid has been considered for use in therapy in certain neurobiological disorders.
High levels of kynurenic acid have been identified in human urine in certain metabolic disorders, such as marked pyridoxine deficiency and deficiency/absence of kynureninase.
|Storage||Prior to and following reconstitution store the protein at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.