discontinued

AR10320PU-L Lambda Light Chain

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10 mg / €2,620.00

Quick Overview

Lambda Light Chain

AR10320PU-L

Product Description for Lambda Light Chain

Lambda Light Chain.
Presentation: Purified

Properties for Lambda Light Chain

Product Category Proteins & Growth Factors
Quantity 10 mg
Presentation Purified
Molecular weight 23 kDa
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 96.0%
Background

Lambda light chain is the smaller of the two types of polypeptide chains in immunoglobulins, consisting of an antigen-binding segment with a variable amino acid sequence, and a constant region with a relatively unchanging amino acid sequence. The lambda light chain gene is located on chromosome 22. The immunoglobulin heavy chains (G, A, M, D, or E) and light chains (kappa or lambda) are produced separately by the plasma cells in the bone marrow. The kappa and lambda molecules are attached to the heavy chains and whole immunoglobulins are assembled, and then conveyed to the surface of the plasma cell. Small amounts of free kappa and lambda light chains are found in the serum of healthy individuals since they are produced in excess. An accurate measurement of serum levels of free light chains in the presence of a great excess of bound light chains has been quite tricky for many years due to their identical structure. A number of diseases affect the production of free light chains by the plasma cells in the bone marrow, causing abnormal levels in the serum, urine or cerebrospinal fluid.
Lambda along with kappa light chains can be used as a tumor marker in urine.

Storage

Store undiluted at 2 8°C.
Shelf life: one year from despatch.

Source Human Urine
Description
Description:
Human Lambda light chain produced in Human Urine.
Format
Buffer System:
Lyophilized from 0.02M NH4HCO3
Purity:
> 96.0%
State:
Sterile Filtered White lyophilized (freeze-dried) powder
Purified
Reconstitution:
Restore in Sodium Acetate buffer at pH 4.0 containing 0.5M NaCl
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