discontinued

AR10215PU-L Leuprolide

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0.1 g / €710.00

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Leuprolide

AR10215PU-L

Product Description for Leuprolide

Leuprolide.
Presentation: Purified

Properties for Leuprolide

Product Category Proteins & Growth Factors
Quantity 0.1 g
Presentation Purified
Molecular weight 1209 Da
Source Synthetic
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98.0% as determined by RP-HPLC
Background

Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH agonist).
By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH).
Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF. 

Concentration 1.0 mg/ml (prior to lyophil.)
Storage

Prior to reconstitution store at 2-8°C for one month or desiccated below -18°C.
Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Source Synthetic
Description
Description:
Synthetic Human Leuprolide is a single, non-glycosylated, polypeptide chain containing 9 amino acids.
AA Sequence:
Glu-His-Trp-Ser-Tyr-DLeu-Leu-Arg-Pro-NHEt
Format
Purity:
> 98.0% as determined by RP-HPLC
State:
Sterile Filtered White lyophilized (freeze-dried) powder without additives
Purified
Reconstitution:
Restore in sterile 18MΩ-cm-1 H2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.
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