AR50630PU-S LGALS3 (1-264, His-tag)

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50 µg / €370.00
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Quick Overview

LGALS3

Product Description for LGALS3

LGALS3.
Presentation: Purified

Properties for LGALS3

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms CBP35, GAL3, GALBP, GALIG, LGALS2, Lectin, MAC2., galactose binding, soluble 3
Presentation Purified
Molecular weight 29.8 kDa
Source E. coli
Species (Protein) Mouse
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q8C253
Purity > 95 % by SDS - PAGE
Background LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Barondes SH., et al. (1994) J Biol Chem. 269(33):20807-10.Kadrofske MM., et al. (1998) Arch Biochem Biophys. 349(1):7-20.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant mouse LGALS3 protein, used to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAP GAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRF NENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI
Molecular weight:
(287aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol,1mM DTT, 2mM EDTA
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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