Product Description for LGALS3
Properties for LGALS3
|Product Category||Proteins & Growth Factors|
|Synonyms||CBP35, GAL3, GALBP, GALIG, LGALS2, Lectin, MAC2, galactose binding, soluble 3|
|Molecular weight||29.8 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 95 % by SDS - PAGE|
|Background||LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombint mouse LGALS3 protein, used to His-tag at N-terminus, was expressed in E.coli and purified by using conventiol chromatography techniques.|
|Concentration||0.5 mg/ml (determined by bradford assay)|
|General Readings||Barondes SH., et al. (1994) J Biol Chem. 269(33):20807-10.Kadrofske MM., et al. (1998) Arch Biochem Biophys. 349(1):7-20.|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.