Product Description for Lgals7
Properties for Lgals7
|Product Category||Proteins & Growth Factors|
|Molecular weight||17.6 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 95 % by SDS - PAGE|
|Background||Lglas7, also known as galectin7, is a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Members of this family have been implicated in a variety of functions, including growth regulation, cell adhesion, migration, neoplastic transformation, and immune responses. It is expressed mainly in stratified squamous epithelium. Lgals7 protein is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. Recombinant mouse Lgals7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques|
|Concentration||1 mg/ml (determined by Bradford assay)|
|General Readings||Magnaldo T., et al. (1995) Dev Biol. 168(2):259-71. Magnaldo T., et al. (1998) Differentiation. 63(3):159-68.|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.