AR09388PU-N MAT1A (1-395, His-tag)

Search for all "MAT1A"

50 µg / €370.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

MAT1A

AR09388PU-N

More Views

  • AR09388PU-N

Product Description for MAT1A

MAT1A.
Presentation: Purified

Properties for MAT1A

Product Category Proteins & Growth Factors
Target Category
Quantity 50 µg
Synonyms AMS1, AdoMet synthetase 1, MAT 1, MAT-I/III, MATA1, Methionine adenosyltransferase 1, Methionine adenosyltransferase I/III, S-adenosylmethionine synthetase isoform type-1
Presentation Purified
Molecular weight 45.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q00266
Purity > 95 % by SDS - PAGE
Background MAT1A catalyzes the formation of S-adenosyltransferase (AdoMet) for methionine catabolism in the liver. MAT1A expression also correlates with a differentiated phenotype, whereas liver cells expressing MAT2A present a dedifferentiated phenotype and lowered AdoMet synthesis. Likewise, NFκB and TNFα cause a switch from MAT1A to MAT2A expression in human hepatocellular carcinoma (HCC), which facilitates cancer cell growth.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Tomasi ML., et al. (2009) Gastroenterology. 136(3):1025-36.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human MAT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHS SGLVPRGSHM NGPVDGLCDH SLSEGVFMFT SESVGEGHPD KICDQISDAV LDAHLKQDPN AKVACETVCK TGMVLLCGEI TSMAMVDYQR VVRDTIKHIG YDDSAKGFDF KTCNVLVALE QQSPDIAQCV HLDRNEEDVG AGDQGLMFGY ATDETEECMP LTIILAHKLN ARMADLRRSG LLPWLRPDSK TQVTVQYMQD NGAVIPVRIH TIVISVQHNE DITLEEMRRA LKEQVIRAVV PAKYLDEDTV YHLQPSGRFV IGGPQGDAGV TGRKIIVDTY GGWGAHGGGA FSGKDYTKVD RSAAYAARWV AKSLVKAGLC RRVLVQVSYA IGVAEPLSIS IFTYGTSQKT ERELLDVVHK NFDLRPGVIV RDLDLKKPIY QKTACYGHFG RSEFPWEVPR KLVF
Molecular weight:
(414 aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 0.1 M NaCl, 10% glycerol
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
  • LinkedIn