AR51246PU-N MDS1 (1-169, His-tag)

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0.1 mg / €730.00
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Quick Overview

MDS1

Product Description for MDS1

MDS1.
Presentation: Purified

Properties for MDS1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms MDS1-EVI1, Myelodysplasia syndrome 1, PRDM3
Presentation Purified
Molecular weight 21.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q6FH90
Purity > 85 % by SDS - PAGE
Background MDS1 is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. Recombinant human MDS1 protein, fused to His-tag at N-terminus, was expressed in E.coli
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Fears S., et al. (1996) Proc. Natl. Acad. Sci. U.S.A. 93:1642-1647.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAP IYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS
Molecular weight:
(192aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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