PA1192 Menopausal Gonadotropin

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Menopausal Gonadotropin


Product Description for Menopausal Gonadotropin

Menopausal Gonadotropin.
Presentation: Purified

Properties for Menopausal Gonadotropin

Product Category Proteins & Growth Factors
Quantity 1 mg
Presentation Purified
Source Urine
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98 % Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Add. information Protein quantitation was carried out by two independent methods:
1. UV spectroscopy at 280 nm .
2. Analysis by RP-HPLC, using a standard solution of hMG as a Reference Standard.

Free of: HbsAg, Hepatitis B surface antigen and antibodies to HIV, Hepatitis C and HCV.
Concentration 1.0 mg/ml
General Readings
  1. Lin YH, Seow KM, Chen HJ, Huang LW, Hwang JL, Tzeng CR. Impact of estradiol patterns in clomiphene citrate/human menopausal gonadotropin/cetrorelix protocol. Gynecol Endocrinol. 2007 Jan;23(1):45-9. PubMed PMID: 17484512.
  2. Zhang HQ, Yan B, Zhao HX, Gu DY, Jia XF, Cao L, et al. Effect of traditional Chinese herbs combined with low dose human menopausal gonadotropin applied in frozen-thawed embryo transfer. Chin J Integr Med. 2006 Dec;12(4):244-9. PubMed PMID: 17361518.
  3. Lin YH, Hwang JL, Seow KM, Huang LW, Hsieh BC, Tzeng CR. Comparison of outcome of clomiphene citrate/human menopausal gonadotropin/cetrorelix protocol and buserelin long protocol--a randomized study. Gynecol Endocrinol. 2006 Jun;22(6):297-302. PubMed PMID: 16785154.
  4. Zech NH, Netzbandt P, Zech H. Development of severe ovarian hyperstimulation syndrome after inadvertent stimulation with a gonadotropin-releasing hormone agonist and human menopausal gonadotropin in a pre-existing early pregnancy. Fertil Steril. 2005 Dec;84(6):1745. PubMed PMID: 16359980.
  5. Keye WR, Webster B, Dickey R, Somkuti S, Crain J, Scobey MJ. Subcutaneously administered Menopur, a new highly purified human menopausal gonadotropin, causes significantly fewer injection site reactions than Repronex in subjects undergoing in vitro fertilization. Reprod Biol Endocrinol. 2005 Nov 9;3:62. PubMed PMID: 16280073. (Free PMC Article available, 1 images available)
  6. Ov ulation induction in the new millennium: recombinant follicle-stimulating hormone versus human menopausal gonadotropin. Gynecol Endocrinol 2005 Mar;20(3):161-9
Storage Lyophilized hMG although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution hMG should be stored at 4 C between 2-7 days and for future use below -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles.
Source Urine of post-menopausal women.
hMG is produced from a sterile preparation of placental glucoprotein urine of post-menopausal women.The hMG is purified by proprietary chromatographic techniques.
Biological activity:
hMG conforms the following activities:
100 IU/mg of FSH and 100IU/mg LH.
Buffer System:
Lyophilized from a concentrated solution in water containing no additives.
>98% Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Sterile Filtered White lyophilized (freeze-dried) powder.
It is recommended to reconstitute the lyophilized hMG in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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