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0.1 g / €1,540.00

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Product Description for MOG

Presentation: Purified

Properties for MOG

Product Category Proteins & Growth Factors
Quantity 0.1 g
Presentation Purified
Molecular weight 2582 Da
Source Synthetic
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98.0% as determined by both RP-HPLC and SDS-PAGE analysis

MOG is a transmembrane protein expressed on the surface of oligodendrocyte cell and on the outermost surface of myelin sheaths. MOG comprises about 0.1% of total CNS myelin protein. The MOG gene is a member of the immunoglobulin gene superfamily and is found within the MHC. The MOG gene is found on chromosome 6p21.3-p22.
Myelin Oligodendrocyte Glycoprotein is a glycoprotein thought to be significant in the process of myelinization of nerves in the central nervous system (CNS).
MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses.
A single injection of this peptide produces a relapsing- remitting neurologic disease with extensive plaque-like demyelination.
Because of the clinical, histophathologic, and immunologic similarities with multiple sclerosis (MS), the MOG induced demyelinating encephalomyelitis may serve as a model for investigating MS.

Storage Prior to reconstitution store at 2-8°C. 
Following reconstitution store undiluted at 2-8°C for one week or (in aliquots) at -20°C for longer. 
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Source Synthetic
Myelin Oligodendrocyte Glycoprotein is a single, non-glycosylated polypeptide chain containing 21 amino acids. 
Amino Acid Composition: H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH.
> 98.0% as determined by both RP-HPLC and SDS-PAGE analysis
Sterile Filtered White lyophilized (freeze-dried) powder with no additives
Restore in sterile 18MΩ-cm-1 H2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions
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