AR50718PU-N MYD88 (1-309, His-tag)

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0.5 mg / €730.00
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Quick Overview

MYD88

Product Description for MYD88

MYD88.
Presentation: Purified

Properties for MYD88

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms Myeloid differentiation primary response protein MyD88
Presentation Purified
Molecular weight 38.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q99836
Purity > 90 % by SDS - PAGE
Background Myeloid differentiation primary response gene 88, also known as MYD88, acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Kawai T., et al. (2004) Nat. Immunol A. 5:1061-1068Semaan N., et al. (2008) J. Immunol. 180:3485-3491
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human MYD88 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMRPD RAEAPGPPAM AAGGPGAGSA APVSSTSSLP LAALNMRVRR RLSLFLNVRT QVAADWTALA EEMDFEYLEI RQLETQADPT GRLLDAWQGR PGASVGRLLE LLTKLGRDDV LLELGPSIEE DCQKYILKQQ QEEAEKPLQV AAVDSSVPRT AELAGITTLD DPLGHMPERF DAFICYCPSD IQFVQEMIRQ LEQTNYRLKL CVSDRDVLPG TCVWSIASEL IEKRCRRMVV VVSDDYLQSK ECDFQTKFAL SLSPGAHQKR LIPIKYKAMK KEFPSILRFI TVCDYTNPCT KSWFWTRLAK ALSLP
Molecular weight:
(345aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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