AR50086PU-N NFKBIA / IKBA (1-317, His-tag)

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0.25 mg / €940.00
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NFKBIA / IKBA

Product Description for NFKBIA / IKBA

NFKBIA / IKBA.
Presentation: Purified

Properties for NFKBIA / IKBA

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms I kappa B-alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI
Presentation Purified
Molecular weight 37.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P25963
Purity > 90 % by SDS - PAGE
Background NF-kappa-B inhibitor alpha, also known as NFKBIA, is members of the IkB family of proteins can be divided into four groups (IkB-alpha, IkB-beta, IkB-gamma, IkB-epsilon). NFKBIA inhibits the NFkB complex by binding and sequestering it in the cytoplasm. Upon stimulation, NFKBIA is phosphorylated on serine residues marking it for degradation by the ubiquitin pathway.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Simson C S., et al. (2000) J Biol Chem. 275:16879-16884.Singh S., et al. (1996) J Biol Chem. 271:31049-31054.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human NFKBIA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MFQAAERPQE WAMEGPRDGL KKERLLDDRH DSGLDSMKDE EYEQMVKELQ EIRLEPQEVP RGSEPWKQQL TEDGDSFLHL AIIHEEKALT MEVIRQVKGD LAFLNFQNNL QQTPLHLAVI TNQPEIAEAL LGAGCDPELR DFRGNTPLHL ACEQGCLASV GVLTQSCTTP HLHSILKATN YNGHTCLHLA SIHGYLGIVE LLVSLGADVN AQEPCNGRTA LHLAVDLQNP DLVSLLLKCG ADVNRVTYQG YSPYQLTWGR PSTRIQQQLG QLTLENLQML PESEDEESYD TESEFTEFTE DELPYDDCVF GGQRLTL
Molecular weight:
(337aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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