AR50772PU-N OCT4 (1-265, His-tag)

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0.5 mg / €940.00
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Quick Overview

OCT4

Product Description for OCT4

OCT4.
Presentation: Purified

Properties for OCT4

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms MGC22487, OCT3, OCT4, OTF3, OTF4, POU domain, POU5F1, class 5, transcription factor 1 isoform 2
Presentation Purified
Molecular weight 32.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
M1S623
Purity > 85 % by SDS - PAGE
Background POU domain, class 5, transcription factor 1, also known as OCT4, binds to the octamer motif (5'-ATTTGCAT-3'). This protein forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Takahashi K., et al. (2007) Cell. 131:861-872Lee J., et al. (2008) Int. J. Biochem. Cell Biol. 40:1043-1054
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human OCT4 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MHFYRLFLGA TRRFLNPEWK GEIDNWCVYV LTSLLPFKIQ SQDIKALQKE LEQFAKLLKQ KRITLGYTQA DVGLTLGVLF GKVFSQTTIC RFEALQLSFK NMCKLRPLLQ KWVEEADNNE NLQEICKAET LVQARKRKRT SIENRVRGNL ENLFLQCPKP TLQQISHIAQ QLGLEKDVVR VWFCNRRQKG KRSSSDYAQR EDFEAAGSPF SGGPVSFPLA PGPHFGTPGY GSPHFTALYS SVPFPEGEAF PPVSVTTLGS PMHSN
Molecular weight:
(285aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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