PA1195X Octreotide (Synthetic)

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Product Description for Octreotide

Presentation: Purified

Properties for Octreotide

Product Category Proteins & Growth Factors
Quantity 5 mg
Presentation Purified
Source Synthetic
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98 % as determined by RP-HPLC.
Background Octreotide acetate is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone.
Concentration 1.0 mg/ml
General Readings 1. The role of octreotide versus placebo in the prevention of post-ERCP pancreatitis.
Hepatogastroenterology 2007 Jan-Feb;54(73):250-3
2. Octreotide for esophageal variceal bleeding treated with endoscopic sclerotherapy: a randomized, placebo-controlled trial. Hepatogastroenterology 2007 Jan-Feb;54(73):195-200
3. 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT. J Nucl Med 2007 Apr;48(4):508-18
4. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate. Gastroenterology 2007 Mar;132(3):1104-16
5. Administration of octreotide for management of postoperative high-flow chylothorax. Ann Vasc Surg 2007 Jan;21(1):90-2
6. Octreotide LAR for severe obscure-overt gastrointestinal haemorrhage in high-risk patients on anticoagulation therapy. Gut 2007 Mar;56(3):447
Storage Lyophilized Octreotide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C.
Reconstituted Octreotide is best stored refrigerated at 4°C for 2-7 days and below -18°C for longer.
For long term storage it is recommended to add a carrier protien (0.1% HSA or BSA).
Please avoid freeze-thaw cycles.
Synthetic Human Octreotide is a single, non-glycosylated, polypeptide chain containing 8 amino acids, having a molecular mass of 1019.26 Dalton and a molecular formula of C49H66N10O10S2 .Octreotide is purified by proprietary chromatographic techniques.
AA Sequence:
The sequence was determined to be H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol.
Molecular weight:
1019.26 Dalton
Buffer System:
Octreotide was lyophilized from a concentrated solution with no additives.
>98% as determined by RP-HPLC.
Sterile Filtered White lyophilized (freeze-dried) powder.
It is recommended to reconstitute the lyophilized Octreotide in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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