discontinued

PA1195XC Octreotide (Synthetic)

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25 mg / €760.00

Quick Overview

Octreotide

PA1195XC

Product Description for Octreotide

Octreotide.
Presentation: Purified

Properties for Octreotide

Product Category Proteins & Growth Factors
Quantity 25 mg
Presentation Purified
Source Synthetic
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98 % Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Background Octreotide acetate is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone.
Concentration 1.0 mg/ml
General Readings 1. The role of octreotide versus placebo in the prevention of post-ERCP pancreatitis.
Hepatogastroenterology 2007 Jan-Feb;54(73):250-3
2. Octreotide for esophageal variceal bleeding treated with endoscopic sclerotherapy: a randomized, placebo-controlled trial. Hepatogastroenterology 2007 Jan-Feb;54(73):195-200
3. 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT. J Nucl Med 2007 Apr;48(4):508-18
4. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate. Gastroenterology 2007 Mar;132(3):1104-16
5. Administration of octreotide for management of postoperative high-flow chylothorax. Ann Vasc Surg 2007 Jan;21(1):90-2
6. Octreotide LAR for severe obscure-overt gastrointestinal haemorrhage in high-risk patients on anticoagulation therapy. Gut 2007 Mar;56(3):447
Storage Lyophilized Octreotide although stable at room temperature, should be stored desiccated below 0°C. Reconstituted Octreotide is best stored refrigerated at 4°C. Please avoid freeze-thaw cycles.
Description
Description:
Synthetic Human Octreotide is a single, non-glycosylated, polypeptide chain containing 8 amino acids, having a molecular formula of C49H66N10O10S2 .Octreotide is purified by proprietary chromatographic techniques.
AA Sequence:
The sequence was determined to be H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol.
Molecular weight:
1019.26 Dalton
Format
Buffer System:
Octreotide was lyophilized from a concentrated solution with no additives.
Purity:
>98% Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
State:
Sterile Filtered White lyophilized (freeze-dried) powder.
Purified
Reconstitution:
It is recommended to reconstitute the lyophilized Octreotide in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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