AR09137PU-N Osteoprotegerin / TNFRSF11B (22-401, His-tag)

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0.15 mg / €1,000.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Osteoprotegerin / TNFRSF11B

Product Description for Osteoprotegerin / TNFRSF11B

Osteoprotegerin / TNFRSF11B.
Presentation: Purified

Properties for Osteoprotegerin / TNFRSF11B

Product Category Proteins & Growth Factors
Target Category
Quantity 0.15 mg
Synonyms OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
Presentation Purified
Molecular weight 44.7 kDa
Source Insect cells
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
O00300
Purity > 90 % by SDS - PAGE
Add. information (On SDS-PAGE under denatured condition, apparent molecular weight of glycosylated rhOPG protein will be appeared at approximately 55kDa).
Background Osteoprtegerin (OPG) is a member of the tumor necrosis factor (TNF)-related family, is referred to as TNFRSF11B and part of the OPG/receptor activator of NF-кB ligand (RANKL)/receptor activator of NF-кB (RANK) triad. This cytokine that lacks any apparent cell-association motifs and exists as a soluble secreted protein, network regulates the differentiation and activation of osteoclasts and hence the critical balance between bone formation (osteoblasts) and bone resorption (osteoclasts).
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings A. Van Campenhout, Golledge J. (2009) Atherosclerosis 204:321-29.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human osteoprotegerin protein, fused to His-tag at C-terminus, was expressed in insect cell using baculovirus expression system and purified by using conventional chromatography techniques.
AA Sequence:
ADPETFPPKY LHYDEETSHQ LLCDKCPPGT YLKQHCTAKW KTVCAPCPDH YYTDSWHTSD ECLYCSPVCK ELQYVKQECN RTHNRVCECK EGRYLEIEFC LKHRSCPPGF GVVQAGTPER NTVCKRCPDG FFSNETSSKA PCRKHTNCSV FGLLLTQKGN ATHDNICSGN SESTQKCGID VTLCEEAFFR FAVPTKFTPN WLSVLVDNLP GTKVNAESVE RIKRQHSSQE QTFQLLKLWK HQNKDQDIVK KIIQDIDLCE NSVQRHIGHA NLTFEQLRSL MESLPGKKVG AEDIEKTIKA CKPSDQILKL LSLWRIKNGD QDTLKGLMHA LKHSKTYHFP KTVTQSLKKT IRFLHSFTMY KLYQKLFLEM IGNQVQSVKI SCLHHHHHH
Molecular weight:
(389 aa)
Format
Buffer System:
PBS (pH 7.4) containing 10% glycerol
Endotoxin level:
< 1.0 EU per 1µg of protein (determined by LAL method )
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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