AR09637PU-L PCBD1 (1-104, His-tag)

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0.5 mg / €820.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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PCBD1

AR09637PU-L

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  • AR09637PU-L

Product Description for PCBD1

PCBD1.
Presentation: Purified

Properties for PCBD1

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms DCOH, Dimerization cofactor of HNF1, PCBD, PHS, Phenylalanine hydroxylase-stimulating protein, Pterin carbinolamine dehydratase, Pterin-4-alpha-carbinolamine dehydratase
Presentation Purified
Molecular weight 14.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P61457
Purity > 95 % by SDS - PAGE
Background Pterin-4-alpha-carbinolamine dehydratase precursor, also known as PCBD1, is a component of the phenylalanine hydroxylase (PAH) system and participates in tetrahydrobiopterin biosynthesis. A deficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of the transcription factor hepatocyte nuclear factor 1 (HNF1).
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Schallreuter K U., et al. (2004) Biochem Biophys Res Commun. 315:502-508.
Hasse S., et al. (2005) Exp Dermatol. 14:182-187.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human PCBD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MAGKAHRLSA EERDQLLPNL RAVGWNELEG RDAIFKQFHF KDFNRAFGFM TRVALQAEKL DHHPEWFNVY NKVHITLSTH ECAGLSERDI NLASFIEQVA VSMT
Molecular weight:
(124aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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