Product Description for POLL
Properties for POLL
|Product Category||Proteins & Growth Factors|
|Synonyms||BETA-N, DNA polymerase lambda, POL-KAPPA|
|Molecular weight||36 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 90 % by SDS - PAGE|
|Background||DNA polymerase lambda, also known as POLL, is a DNA polymerase involved in base excision repair (BER). POLL is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. In addition, POLL may play a role in the mutagenic bypass of T-T dimers. Pol lambda possesses terminal transferase and 5'-deoxyribose-5-phosphate lyase activity. These activities have been found to be coordinated by PCNA and replication protein A.|
|Concentration||0.5 mg/ml (determined by Bradford assay)|
|General Readings||O Wang J., et al. (2001) Cancer Res. 61:5366-5369.Zhang Y., et al. (2000) Nucleic Acids Res. 28:4147-4156.|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.