AR50776PU-S POLR2J2 (1-115, His-tag)

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50 µg / €370.00
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Quick Overview

POLR2J2

Product Description for POLR2J2

POLR2J2.
Presentation: Purified

Properties for POLR2J2

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms DNA-directed RNA polymerase II subunit RPB11-b1, HRPB11B, RPB11b1
Presentation Purified
Molecular weight 15.5 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
F6W009
Purity > 95 % by SDS - PAGE
Background POLR2J2 is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Shpakovskii,D.G., et al. (2004) Bioorg. Khim. 30 (6), 621-625Benga,W.J., et al. (2005) Nucleic Acids Res. 33 (11), 3582-3590
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human POLR2J2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMNAPPAF ESFLLFEGEK ITINKDTKVP KACLFTINKE DHTLGNIIKS QLLKDPQVLF AGYKVPHPLE HKIIIRVQTT PDYSPQEAFT NAITDLISEL SLLEERFRTC LLPLRLLP
Molecular weight:
(138aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT, 250mM Imidazole
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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