discontinued

AR10467PU-N Prolactin Antagonist

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50 µg / €300.00

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Prolactin Antagonist

AR10467PU-N

Product Description for Prolactin Antagonist

Prolactin Antagonist.
Presentation: Purified

Properties for Prolactin Antagonist

Product Category Proteins & Growth Factors
Quantity 50 µg
Presentation Purified
Source E. coli
Species (Protein) Sheep
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >98.0% as determined by both RP-HPLC and SDS-PAGE analysis
Background

Prolactin is a lactogenic hormone secreted by the adenohypophysis .Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation.Prolactin has been shown also to have cytokine-like activities and to have important immunoregulatory activities. It contributes to the development of lymphoid tissues and the maintenance of physiological immune function and also modulates a variety of T-cell immune responses. Prolactin has been reported to activate cellular proliferation in nonreproductive tissue, such as liver, spleen, and thymus. It induces significant proliferation in aortic smooth muscle cells and also enhances proliferation of these cells induced by PDGF . Prolactin also appears to be directly mitogenic for pancreatic beta cells. Prolactin is also mitogenic for cultured astrocytes.

Concentration 1.0 mg/ml (prior to lyophil.)
Storage Prior to reconstitution store at 2-8°C for one month or desiccated below -18°C.
Following reconstitution store undiluted at 2-8°C for one month
or (in aliquots) at -20°C for longer. 
 For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Ovine Prolactin Antagonist produced in E.coli is a single, non-glycosylated polypeptide chain.
Ovine Prolactin Antagonist is purified by proprietary chromatographic techniques.
Format
Buffer System:
Lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3
Purity:
>98.0% as determined by both RP-HPLC and SDS-PAGE analysis
State:
Sterile Filtered White lyophilized (freeze-dried) powder
Purified
Reconstitution:
Restore in sterile 18MΩ-cm-1 H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
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