AR10125PU-S Prothrombin Complex

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Prothrombin Complex


Product Description for Prothrombin Complex

Prothrombin Complex.
Presentation: Purified

Properties for Prothrombin Complex

Product Category Proteins & Growth Factors
Quantity 10 IU
Presentation Purified
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract


Prothrombin Complex Concentrate (PCC) is a combination of several blood clotting factors II, VII, IX and X. PCC is used in the treatment of the congenital bleeding disorders associated with Factors II, VII, IX, and X deficiencies. PCC reverses the effect of warfarin (a coumarin anti-coagulant) and is used in cases of significant bleeding in patients with a coagulopathy, for example, gastrointestinal haemorrhage or intracranial haemorrhage. The PCC is also extensively used in treating acquired coagulation abnormalities secondary to vitamin K deficiency, warfarin ingestion, and various types of liver disease.
Hepatitis, anaphylaxis and thrombosis have been reported as complications of prothrombin complex concentrates administration.

Storage Lyophilized Prothrombin-Complex although stable at RT for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Prothrombin-Complex should be stored at 2-8°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
Avoid repeated freezing and thawing. 
Shelf life: One year from despatch.
Prothrombin complex is a double virus-inactivated concentrate, containing equal Concentrations of Factors II, VIII, IX, X and Heparin.
Buffer System:
Lyophilized Powder from 0.1M Sodium Chloride and 10mM Sodium Citrate buffer.
Sterile Filtered White lyophilized (freeze-dried) powder.
Restore in sterile 18MΩ-cm-1 H2O.
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