AR09643PU-L PTP4A2 (1-167, His-tag)

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0.25 mg / €1,000.00
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PTP4A2

AR09643PU-L

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  • AR09643PU-L

Product Description for PTP4A2

PTP4A2.
Presentation: Purified

Properties for PTP4A2

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms HU-PP-1, OV-1, PRL-2, PRL2, PTPCAAX2, Protein tyrosine phosphatase type IVA 2, Protein-tyrosine phosphatase 4a2, Protein-tyrosine phosphatase of regenerating liver 2
Presentation Purified
Molecular weight 23.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q12974
Purity > 90 % by SDS - PAGE
Background Protein tyrosine phosphatase type IVA 2 isoform 1, also known as PTP4A2, belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that play regulatory roles in a variety of cellular processes. This protein was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Si X., et al. (2001) J Biol chem. 246(35):32875-82.
Werner SR., et al. (2003) Cancer Lett. 202(2):201-11.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human PTP4A2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNRP APVEISYENM RFLITHNPTN ATLNKFTEEL KKYGVTTLVR VCDATYDKAP VEKEGIHVLD WPFDDGAPPP NQIVDDWLNL LKTKFREEPG CCVAVHCVAG LGRAPVLVAL ALIECGMKYE DAVQFIRQKR RGAFNSKQLL YLEKYRPKMR LRFRDTNGHC CVQ
Molecular weight:
(203aa), confirmed by MALDI-TOF
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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