NBP1-43167-25 RANKL Protein

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RANKL Protein


Product Description for RANKL Protein

RANKL Protein.
Presentation: Purified

Properties for RANKL Protein

Product Category Proteins & Growth Factors
Quantity 25 µg
Presentation Purified
Reactivity Eq, Hu
Molecular weight 20 kDa
Species (Protein) Human
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Swiss Prot Num:
Background RANK Ligand (Receptor Activator for Nuclear Factor kappaB Ligand), also known as TNF-related activation-induced cytokine (TRANCE), along with RANK are members of the TNF superfamily. RANK-L can be found as a soluble protein expressed by activated T lymphocytes, which plays a role in dendritic cell maturation. In addition it has also been shown to be cleaved by TACE (TNF-alpha convertase) releasing an ectodomain variant of the cell bound form. Lastly RANK-L is expressed as a Type II transmembrane protein expressed by osteoblast lineages. The receptor RANK, located on osteoclastic and dendritic cells can recognize all forms of RANK-L. RANK-L plays a critical role in bone development and mineralization. High levels of RANK-L have been associated with degenerative bone diseases.
Storage Store at -80C. Avoid freeze-thaw cycles.
Buffer System:
Sterile liquid, phosphate buffered saline, pH 7.2, with 1.0% BSA. 0.22um filtered.
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