AR09774PU-L ROBLD3 (1-125, His-tag)

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0.5 mg / €1,000.00
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ROBLD3

AR09774PU-L

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  • AR09774PU-L

Product Description for ROBLD3

ROBLD3.
Presentation: Purified

Properties for ROBLD3

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms Endosomal adaptor protein p14, HSPC003, Late endosomal/lysosomal Mp1-interacting protein, MAPBPIP, Mitogen-activated protein-binding protein-interacting protein, Roadblock domain-containing protein 3
Presentation Purified
Molecular weight 16 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y2Q5
Purity > 95 %
Background ROBLD3, also known as MAPBPIP, belongs to the GAMAD family. It is an adapter protein that enhances the efficiency of the MAP kinase cascade and facilitates the activation of MAPK2. ROBLD3 compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Sancak Y., et al. (2010) Cell. 141(2):290-303.
Waters S., et al. (2009) FEBS Lett. 583(12):1846-52.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human ROBLD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMLRPKA LTQVLSQANT GGVQSTLLLN NEGSLLAYSG YGDTDARVTA AIASNIWAAY DRNGNQAFNE DNLKFILMDC MEGRVAITRV ANLLLCMYAK ETVGFGMLKA KAQALVQYLE EPLTQVAAS
Molecular weight:
(149aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 2mM DTT, 10% glycerol
Purity:
>95%
State:
Liquid purified protein
Purified
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