AR50891PU-N ROBLD3 (1-125, His-tag)

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0.25 mg / €940.00
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Quick Overview

ROBLD3

Product Description for ROBLD3

ROBLD3.
Presentation: Purified

Properties for ROBLD3

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms Endosomal adaptor protein p14, HSPC003, Late endosomal/lysosomal Mp1-interacting protein, MAPBPIP, Mitogen-activated protein-binding protein-interacting protein, Roadblock domain-containing protein 3
Presentation Purified
Molecular weight 15.9 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y2Q5
Purity > 90 % by SDS - PAGE
Background LAMTOR2 is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Bohn G., et al. (2007) Nat. Med. 13:38-45Sancak Y., et al. (2010) Cell. 141:290-303
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human LAMTOR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMLRPKAL TQVLSQANTG GVQSTLLLNN EGSLLAYSGY GDTDARVTAA IASNIWAAYD RNGNQAFNED NLKFILMDCM EGRVAITRVA NLLLCMYAKE TVGFGMLKAK AQALVQYLEE PLTQVAAS
Molecular weight:
(148aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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