AR09212PU-L SERPINB5 / Maspin (1-375, His-tag)

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0.5 mg / €750.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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SERPINB5 / Maspin

AR09212PU-L

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  • AR09212PU-L

Product Description for SERPINB5 / Maspin

SERPINB5 / Maspin.
Presentation: Purified

Properties for SERPINB5 / Maspin

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms PI-5, PI5, Peptidase inhibitor 5, Protease inhibitor 5, Serpin B5
Presentation Purified
Molecular weight 44.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P36952
Purity > 95 % by SDS - PAGE
Background Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Lockett J., et al. (2006). J Cell Biochem. 97(4):651-60.
Khalkhali Ellis Z., et al. (2006). Clin Cancer Res. 12(24):7279-83.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human Maspin, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDVPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRVNKT DTKPVQMMNM EATFCMGNID SINCKIMELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP
Molecular weight:
(395 aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT,
10% glycerol
Endotoxin level:
< 1.0 EU per 1 µg of protein (determined by LAL method )
Purity:
>95% by SDS - PAGE
State:
Liquid purified protein
Purified
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