AR09256PU-N Serum Amyloid A protein (SAA) (19-122, His-tag)

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0.1 mg / €230.00
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Serum Amyloid A protein (SAA)

Product Description for Serum Amyloid A protein (SAA)

Serum Amyloid A protein (SAA).
Presentation: Purified

Properties for Serum Amyloid A protein (SAA)

Product Category Proteins & Growth Factors
Target Category
Quantity 0.1 mg
Synonyms SAA1, SAA2
Presentation Purified
Molecular weight 13.9 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P02735
Purity > 95 % pure by SDS-PAGE
Background Serum amyloid A1 (SAA1) protein is made primarily in the liver and circulates in low levels in the blood. This protein appears to play a role in the immune system. Levels of this protein increase in the blood and other tissues under conditions of inflammation. SAA1 may help repair damaged tissues, acts as an antibacterial agent, and signal the migration of germ-fighting cells to sites of infection. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid arthritis.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings
  1. Betts JC, Edbrooke MR, Thakker RV, Woo P. The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells. Scand J Immunol. 1991 Oct;34(4):471-82. PubMed PMID: 1656519.
  2. Yilmaz E, Balci B, Kutlay S, Ozen S, Ertürk S, Oner A, et al. Analysis of the modifying effects of SAA1, SAA2 and TNF-alpha gene polymorphisms on development of amyloidosis in FMF patients. Turk J Pediatr. 2003 Jul-Sep;45(3):198-202. PubMed PMID: 14696796.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant Serum amyloid A protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
Molecular weight:
(125 aa), confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris buffer (pH 8.0) containing 10% Glycerol
Purity:
>95% pure by SDS-PAGE
State:
Liquid purified protein
Purified
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