AR09213PU-L Skeletal muscle Troponin C (1-160)

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0.5 mg / €750.00
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Skeletal muscle Troponin C

AR09213PU-L

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  • AR09213PU-L

Product Description for Skeletal muscle Troponin C

Skeletal muscle Troponin C.
Presentation: Purified

Properties for Skeletal muscle Troponin C

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms TNNC2
Presentation Purified
Molecular weight 18.1 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P02585
Purity > 95 % by SDS - PAGE
Background Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Li Y., et al. (2008). Hereditas. 145(6):274-82.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human Troponin C was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ
Molecular weight:
(160 aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 100 mM NaCl, 10% glycerol
Purity:
>95% by SDS - PAGE
State:
Purified
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