Skeletal muscle Troponin C (1-160) - AR09213PU-N

Product Description for Skeletal muscle Troponin C

Skeletal muscle Troponin C.
Presentation: Purified

Product Category	Proteins & Growth Factors
Target Category	Skeletal muscle Troponin C antibody
Quantity	0.1 mg
Synonyms	TNNC2
Presentation	Purified
Molecular weight	18.1 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P02585
Purity	> 95 % by SDS - PAGE
Background	Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Li Y., et al. (2008). Hereditas. 145(6):274-82.
Storage	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human Troponin C was expressed in E.coli and purified by using conventional chromatography. AA Sequence: `MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ` Molecular weight: (160 aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 100 mM NaCl, 10% glycerol Purity: >95% by SDS - PAGE State: Purified