Product Description for Skeletal muscle Troponin C
Skeletal muscle Troponin C.
Presentation: Purified
Presentation: Purified
Properties for Skeletal muscle Troponin C
Product Category | Proteins & Growth Factors |
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Target Category | |
Quantity | 0.1 mg |
Synonyms | TNNC2 |
Presentation | Purified |
Molecular weight | 18.1 kDa |
Source | E. coli |
Species (Protein) | Human |
Shipping to | Worldwide |
PDF datasheet | View Datasheet |
Manufacturer | OriGene Technologies GmbH |
Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
Immunogen |
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Purity | > 95 % by SDS - PAGE |
Background | Troponin C, skeletal muscle, also known as TNNC2, is the central regulatory protein of striated muscle contraction, and modulates the Ca2+-activation characteristics of muscle fibers. Troponin has 3 subunits, Troponin I(Tn-1), Troponin T(Tn-T) and Troponin C(Tn-C). Tn-I subunit inhibits actomyosin ATPase and Tn-T subunit binds tropomyosin and Tn-C, while Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. Mutations in all components of this complex have been associated with skeletal muscle disease. |
Concentration | 1 mg/ml (determined by Bradford assay) |
General Readings | Li Y., et al. (2008). Hereditas. 145(6):274-82. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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