GTX25349 STAT1 (pTyr701) (Phospho and Non-phospho Pair)

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1 packs / €370.00

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Product Description for STAT1


Properties for STAT1

Product Category Proteins & Growth Factors
Quantity 1 packs
Synonyms DKFZP686B04100, ISGF-3, P84, P91, STAT-1, STAT91, Signal Transducer And Activator Of Transcription 1 91kDa, Transcription Factor ISGF-3 Components P91/P84
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Background STATs (signal transducers and activators of transcription) were originally discovered as two proteins (STAT1 and STAT2) which were involved in interferon alpha (IFN alpha) and IFN gamma signal transduction. Since then, several additional STAT proteins have been identified (STAT3, 4, 5a, 5b, and 6). STATs undergo tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. In some cases this process is mediated by JAK Kinases (Janus Kinases 1, 2, and 3). For maximum activation of these proteins, phosphorylation at specific tyrosine and serine residues may be required in STAT1 alpha, 3, 4, and 5.
Buffer System:
Lyophilized powder with trifluoroacetate salt.
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