discontinued

PA1125XC Stem Cell Factor (SCF)

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1 mg / €2,130.00

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Stem Cell Factor (SCF)

PA1125XC

Product Description for Stem Cell Factor (SCF)

Stem Cell Factor (SCF).
Presentation: Purified

Properties for Stem Cell Factor (SCF)

Product Category Proteins & Growth Factors
Quantity 1 mg
Presentation Purified
Molecular weight 18 kDa
Source E. coli
Species (Protein) Mouse
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity > 98 % is greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. Endotoxin is less than. 0.1 ng/µg (IEU/µg) of Murine SCF.
Dimers / aggregates:
Less tha
General Readings 1. Reduced stem cell factor links smooth myopathy and loss of interstitial cells of cajal in murine diabetic gastroparesis. Gastroenterology 2006 Mar;130(3):759-70
2. Bcl-2 reduced and fas activated by the inhibition of stem cell factor/KIT signaling in murine melanocyte precursors. J Invest Dermatol 2005 Jan;124(1):229-34
3. In vitro induction of inhibitory macrophage differentiation by granulocyte-macrophage colony-stimulating factor, stem cell factor and interferon-gamma from lineage phenotypes-negative c-kit-positive murine hematopoietic progenitor cells.
Immunol Lett 2004 Feb 15;91(2-3):221-7
4. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice.
Mol Cell Biol 2004 Feb;24(3):1256-69
5. Enhanced antileukemic activity of allogeneic peripheral blood progenitor cell transplants following donor treatment with the combination of granulocyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) in a murine transplantation model. Bone Marrow Transplant 2003 Jul;32(1):49-56
6. Increment of murine spermatogonial cell number by gonadotropin-releasing hormone analogue is independent of stem cell factor c-kit signal.
Biol Reprod 2003 Jun
Storage Lyophilized Mouse SCF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution rmSCF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze-thaw cycles. Shelf life: one year from despatch.
Source E. coli
Description
Description:
Recombinant murine SCF produced in E.Coli is a single, non-glycosylated polypeptide chain containing 164 amino acids and having a molecular mass of 18309 Dalton. The SCF is purified by proprietary chromatographic techniques. Format: rmSCF is supplied as sterile filtered white freeze-dried powder. It was lyophilized from a concentrated (1 mg/ml) solution in water containing 10 mM Sodium phosphate buffer pH = 6.5 . It is recommended to reconstitute the lyophilized rmSCF in sterile 18M-cm H2O not less than 100 µg/ml, which can then be further diluted with other aqueous solutions. Protein quantitation was carried out by: 1. UV spectroscopy at 280 nm using the absorbency value of 0.52 as the extinction coefficient for a 0.1% (1 mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a standard solution of SCF as a Reference Standard.
Format
Purity:
>98% is greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. Endotoxin is less than. 0.1 ng/µg (IEU/µg) of Murine SCF.
Dimers / aggregates:
Less tha
State:
Purified
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