AR51917PU-N TIMP1 (24-207, His-tag)

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0.25 mg / €940.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

TIMP1

Product Description for TIMP1

TIMP1.
Presentation: Purified

Properties for TIMP1

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms CLGI, EPA, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, Metalloproteinase inhibitor 1, TIMP, TIMP-1, Tissue inhibitor of metalloproteinases
Presentation Purified
Molecular weight 21.5 kDa
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P01033
Purity > 90 % by SDS - PAGE
Background TIMP1, also known as TIMP metalloproteinase inhibitor 1, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.
Concentration 0.2 mg/ml (determined by bradford)
General Readings Ma J, et al (2013) Int J Clin Exp Pathol. 7(1):246-54.Tarhini AA, et al (2014) J Transl Med. 12:19.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TIPM1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
AA Sequence:
CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIAHHHHHH
Molecular weight:
(190aa)
Format
Buffer System:
Phosphate buffered saline (pH7.4).
Endotoxin level:
< 1.0 Eu per 1 microgram of protein (determined by LAL method)
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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