AR51823PU-N Transglutaminase-2 (TGM2) (1-687, His-tag)

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0.25 mg / €940.00
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Transglutaminase-2 (TGM2)

Product Description for Transglutaminase-2 (TGM2)

Transglutaminase-2 (TGM2).
Presentation: Purified

Properties for Transglutaminase-2 (TGM2)

Product Category Proteins & Growth Factors
Target Category
Quantity 0.25 mg
Synonyms Protein-glutamine gamma-glutamyltransferase 2, TGase C, TGase-H, Tissue transglutaminase
Presentation Purified
Molecular weight 79.7 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P21980
Purity > 85 % by SDS - PAGE
Background TGM2 also known as Protein-glutamine gamma-glutamyltransferase 2. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Jeong JH.,et al. (2013) J. Korean Med. Sci. 28 (7), 1005-1014
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TGM2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMAEELVL ERCDLELETN GRDHHTADLC REKLVVRRGQ PFWLTLHFEG RNYEASVDSL TFSVVTGPAP SQEAGTKARF PLRDAVEEGD WTATVVDQQD CTLSLQLTTP ANAPIGLYRL SLEASTGYQG SSFVLGHFIL LFNAWCPADA VYLDSEEERQ EYVLTQQGFI YQGSAKFIKN IPWNFGQFED GILDICLILL DVNPKFLKNA GRDCSRRSSP VYVGRVVSGM VNCNDDQGVL LGRWDNNYGD GVSPMSWIGS VDILRRWKNH GCQRVKYGQC WVFAAVACTV LRCLGIPTRV VTNYNSAHDQ NSNLLIEYFR NEFGEIQGDK SEMIWNFHCW VESWMTRPDL QPGYEGWQAL DPTPQEKSEG TYCCGPVPVR AIKEGDLSTK YDAPFVFAEV NADVVDWIQQ DDGSVHKSIN RSLIVGLKIS TKSVGRDERE DITHTYKYPE GSSEEREAFT RANHLNKLAE KEETGMAMRI RVGQSMNMGS DFDVFAHITN NTAEEYVCRL LLCARTVSYN GILGPECGTK YLLNLNLEPF SEKSVPLCIL YEKYRDCLTE SNLIKVRALL VEPVINSYLL AERDLYLENP EIKIRILGEP KQKRKLVAEV SLQNPLPVAL EGCTFTVEGA GLTEEQKTVE IPDPVEAGEE VKVRMDLLPL HMGLHKLVVN FESDKLKAVK GFRNVIIGPA
Molecular weight:
(710aa)
Format
Buffer System:
Liquid, In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT.
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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