AR10498PU-N Treponema pallidum p17

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Treponema pallidum p17


Product Description for Treponema pallidum p17

Treponema pallidum p17.
Presentation: Purified

Properties for Treponema pallidum p17

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >90% pure as determined by 10% PAGE (coomassie staining).
Purification Method: Inclusion bodies.
Application Antigen in ELISA and Western blots, excellent antigen for detection of Tr.pallidum with minimal specificity problems.
Background Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.  
Concentration 1.0 mg/ml

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

The E.coli derived recombinant protein contains the Tr.pallidum p17 immunodominant regions.
Specificity: Immunoreactive with sera of Tr.pallidum -infected individuals.
Buffer System:
10mM Tris-HCl pH 8.0, 1mM EDTA, 1mMDTT, 8M Urea
>90% pure as determined by 10% PAGE (coomassie staining).
Purification Method: Inclusion bodies.
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