discontinued

AR10494PU-N Treponema pallidum TmpA (23-41, 288-325)

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0.5 mg / €660.00

Quick Overview

Treponema pallidum TmpA

AR10494PU-N

Product Description for Treponema pallidum TmpA

Treponema pallidum TmpA.
Presentation: Purified

Properties for Treponema pallidum TmpA

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Presentation Purified
Source E. coli
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Purity >95% pure as determined by 10% PAGE (coomassie staining). 
Purification Method: Proprietary chromatographic technique.
Application This protein binds to murine anti-TmpA protein monoclonal antibodies and Treponema pallidum converted Human Serum polyclonal antibodies in ELISA and Western Elisa.  Dot Blots and Lateral Flow immunochromatographic diagnostics test.
Background

Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue. 

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Description
Description:
The E.coli derived 68kDa recombinant protein contains the Trp. Pallidum TmpA immunodominant regions, 23-41 amino acids and 288-325 amino acids.
Specificity: Immunoreactive with sera of Trp. Pallidum infected individuals.
Format
Buffer System:
10mM Tris-HCl pH8.0, 20mM DDT, 1mM EDTA and 8M Urea
Purity:
>95% pure as determined by 10% PAGE (coomassie staining). 
Purification Method: Proprietary chromatographic technique.
State:
Purified
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