AR50471PU-N Tropomodulin-3 (TMOD3) (1-352, His-tag)

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0.25 mg / €1,070.00
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Quick Overview

Tropomodulin-3 (TMOD3)

Product Description for Tropomodulin-3 (TMOD3)

Tropomodulin-3 (TMOD3).
Presentation: Purified

Properties for Tropomodulin-3 (TMOD3)

Product Category Proteins & Growth Factors
Quantity 0.25 mg
Synonyms U-Tmod, Ubiquitous tropomodulin
Presentation Purified
Molecular weight 42 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9NYL9
Purity > 80 % by SDS - PAGE
Background TMOD3 belongs to the tropomodulin family. Regulation of the actin cytoskeleton by filament capping proteins is critical to myriad dynamic cellular functions. The ability of these proteins to bind both filaments as well as monomers is often central to their cellular functions. The ubiquitous pointed end capping protein TMOD3 acts as a negative regulator of cell migration, yet mechanisms behind its cellular functions are not understood.
Concentration 0.25 mg/ml (determined by Bradford assay)
General Readings Fischer RS., et al. (2006) J Biol Chem. 2006 Nov 24;281(47):36454-65. Epub 2006 Oct 1.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TMOD3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMALPFR KDLEKYKDLD EDELLGNLSE TELKQLETVL DDLDPENALL PAGFRQKNQT SKSTTGPFDR EHLLSYLEKE ALEHKDREDY VPYTGEKKGK IFIPKQKPVQ TFTEEKVSLD PELEEALTSA SDTELCDLAA ILGMHNLITN TKFCNIMGSS NGVDQEHFSN VVKGEKILPV FDEPPNPTNV EESLKRTKEN DAHLVEVNLN NIKNIPIPTL KDFAKALETN THVKCFSLAA TRSNDPVATA FAEMLKVNKT LKSLNVESNF ITGVGILALI DALRDNETLA ELKIDNQRQQ LGTAVELEMA KMLEENTNIL KFGYQFTQQG PRTRAANAIT KNNDLVRKRR VEGDHQ
Molecular weight:
(376aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Purity:
>80% by SDS - PAGE
State:
Liquid purified protein
Purified
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