AR09621PU-N Tropomyosin-1 (TPM1) (1-284, His-tag)

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0.1 mg / €320.00
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Quick Overview

Tropomyosin-1 (TPM1)

Product Description for Tropomyosin-1 (TPM1)

Tropomyosin-1 (TPM1).
Presentation: Purified

Properties for Tropomyosin-1 (TPM1)

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms Alpha-tropomyosin, C15orf13, TMSA, Tropomyosin alpha-1 chain
Presentation Purified
Molecular weight kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P09493
Purity > 90 % by SDS - PAGE
Background TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. TPM1 is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.
Concentration 0.5 mg/ml (determined by Bradford assay)
General Readings Perry SV. (2001) J Muscle Res Cell Motil. 22(1):5-49.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human TPM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEDRSKQLE DELVSLQKKL KGTEDELDKY SEALKDAQEK LELAEKKATD AEADVASLNR RIQLVEEELD RAQERLATAL QKLEEAEKAA DESERGMKVI ESRAQKDEEK MEIQEIQLKE AKHIAEDADR KYEEVARKLV IIESDLERAE ERAELSEGQV RQLEEQLRIM DQTLKALMAA EDKYSQKEDR YEEEIKVLSD KLKEAETRAE FAERSVTKLE KSIDDLEDEL YAQKLKYKAI SEELDHALND MTSM
Molecular weight:
(304aa) , confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Format
Buffer System:
20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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