AR39043PU-L VPS24 (1-222, His-tag)

Search for all "VPS24"

0.5 mg / €750.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

VPS24

AR39043PU-L

More Views

  • AR39043PU-L

Product Description for VPS24

VPS24.
Presentation: Purified

Properties for VPS24

Product Category Proteins & Growth Factors
Target Category
Quantity 0.5 mg
Synonyms CGI-149, CHMP3, Charged multivesicular body protein 3, Chromatin-modifying protein 3, NEDF, Neuroendocrine differentiation factor, Vacuolar protein-sorting-associated protein 24
Presentation Purified
Molecular weight 27.2 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y3E7
Purity > 90 %
Background VPS24, also known as Charged multivesicular body protein 3 (CHMP3), belongs to the vacuolar sorting protein family and function as chromatin modifying proteins. It associates directly with CHMP2 and CHMP4 for the disassembly of ESCRT-III complex in an ATP-dependent manner. During HIV-1 infection, the virus uses the ESCRT-III complex to mediate budding and exocytosis of viral proteins. Overexpression of VPS24 strongly inhibits HIV-1 release.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Muziol T. et al. (2006) Dev. Cell. 10: 821-830.
Bache K.G. et al. (2006) Mol. Biol. Cell 17: 2513-2523.
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Description
Description:
Recombinant human VPS24 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGLFGKTQEK PPKELVNEWS LKIRKEMRVV DRQIRDIQRE EEKVKRSVKD AAKKGQKDVC IVLAKEMIRS RKAVSKLYAS KAHMNSVLMG MKNQLAVLRV AGSLQKSTEV MKAMQSLVKI PEIQATMREL SKEMMKAGII EEMLEDTFES MDDQEEMEEE AEMEIDRILF EITAGALGKA PSKVTDALPE PEPPGAMAAS EDEEEEEEAL EAMQSRLATL RS
Molecular weight:
(242aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
Format
Buffer System:
20mM Tris-HCl buffer (pH8.0) containing 20% glycero, 0.1M NaCl, 1mM DTT
Purity:
>90%
State:
Liquid purified protein
Purified
  • LinkedIn