Product Description for West Nile Virus Pre-M Protein
West Nile Virus Pre-M Protein.
Presentation: Purified
Presentation: Purified
Properties for West Nile Virus Pre-M Protein
Product Category | Proteins & Growth Factors |
---|---|
Quantity | 0.1 mg |
Synonyms | Genome polyprotein antibody, WNVgp1 antibody, West Nile virus antibody, pre M protein antibody |
Presentation | Purified |
Source | E. coli |
Shipping to | Worldwide |
PDF datasheet | View Datasheet |
Manufacturer | Acris Antibodies GmbH |
Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
Purity | 95% pure (SDS-PAGE) |
---|---|
Application | ELISA. Western blot. Lateral flow. |
Background | West Nile Virus is part of the flavivirus family, many of which are capable of causing serious illness in humans. The ssRNA + strand virus is enveloped and spherical with a diameter of 40-50 nm, similar to all flaviviruses. The virion of this virus is a nucleocapsid covered by a lipoprotein envelope. The envelope contains two proteins: the protein M and glycoprotein E. The nucleocapsid is a complex of protein C and mRNA. In immature particles, there are 60 icosaedrally organized trimeric spikes on the surface. Each spike consists of three heterodimers of envelope protein M precursor (prM) and envelope protein E. Inside cells, viral particles will contain a preM particle and E in a complex that matures through proteolytic cleavage and processing in the Golgi apparatus. WNV has three different effects on humans, the first is asymptomatic infection; the second is a mild febrile syndrome termed West Nile Fever; the third is a neuroinvasive disease termed West Nile meningitis or encephalitis. In infected individuals the ratio between the three states is roughly 110:30:1. The main route of human infection is through the bite of an infected mosquito. |
Concentration | 1,0 mg/ml |
Storage | Store the protein undiluted at 2-8°C for one month or (in aliquots) at -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
Description |
|
Format |
|