Product Description for XAB1
Properties for XAB1
|Product Category||Proteins & Growth Factors|
|Synonyms||ATPBD1A, GPN1, GTPase, MBDIN, NTPBP, XPA binding protein 1|
|Molecular weight||44.3 kDa|
|PDF datasheet||View Datasheet|
|Manufacturer||Acris Antibodies GmbH|
|Material safety datasheet||MSDS for Proteins (de)|
|Purity||> 90 % by SDS - PAGE|
|Background||XAB1, as known as GPN1, belongs to the GPN-loop GTPase family. Small GTPases share a biochemical mechanism and act as binary molecular switches. One important function of small GTPases in the cell is nucleocytoplasmic transport of both proteins and RNA. This protein may play a role in DNA repair and may function in activation of transcription. And it forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.|
|Concentration||1mg/ml (determined by Bradford assay)|
|General Readings||Carre C, et al. (2011) Mol Cell Biol. 31(19):3953-62.Forget D, et al. (2010) Mol Cell Proteomics. 9(12):2827-39.|
|Storage||Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.