CCP1576-10mg Ac-[Pro18, Asp21]-Beta-Amyloid (17-21) amide

Search for all "Ac-[Pro18, Asp21]-Beta-Amyloid (17-21) amide"

Properties for Ac-[Pro18, Asp21]-Beta-Amyloid (17-21) amide

Product Category Synthetic Peptides
Quantity 10 mg
Molecular weight 678.79
Source Synthetic
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Cohesion Biosciences Ltd.

Datasheet Extract

Purity > 95 %
Background The pentapeptide Ac-LPFFD-NH2 (iA��5p) is an analog of product [Pro18; Asp21]-Beta-Amyloid (17-21) with small chemical modifications which enhance its stability against proteolytic degradation. iA��5p acts as a ��-sheet breaker peptide and crosses the blood-brain barrier at a higher rate than most proteins and peptides known to be selectively taken up by the brain so that it is assumed that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer`s disease (AD) models is additionally reported for iA��5p.
Storage Shipped at 4°C. Store at -20°C for one year.
Peptide to Ac-[Pro18, Asp21]-Beta-Amyloid (17-21) amide
CAS Number: 339990-02-2
Molecular Formula: C35H46N6O8
Chemical Structure: Ac-Leu-Pro-Phe-Phe-Asp-NH2
Lyophilized powder
  • LinkedIn