CCP1190-5mg Endothelin-1, Human

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Properties for Endothelin-1, Human

Product Category Synthetic Peptides
Quantity 5 mg
Molecular weight 2491.95
Source Synthetic
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Cohesion Biosciences Ltd.

Datasheet Extract

Purity > 95 %
Background Endothelin-1 a 21-amino acid peptide from vascular endothelial cells of different mammalian species is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart lung brain) tissues. Toxic peptides from a snake venom the sarafotoxins show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.
Storage Shipped at 4°C. Store at -20°C for one year.
Peptide to Endothelin-1, Human
CAS Number: 117399-94-7
Molecular Formula: C109H159N25O32S5
Chemical Structure: H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bridge Cys1-Cys15, Cys3-Cys11)
Lyophilized powder
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