CCP1738-5mg [Phe17]-Apelin 17

Search for all "[Phe17]-Apelin 17"

Properties for [Phe17]-Apelin 17

Product Category Synthetic Peptides
Quantity 5 mg
Molecular weight 2138.59
Source Synthetic
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Cohesion Biosciences Ltd.

Datasheet Extract

Purity > 95 %
Background Apelin-17 is an endogenous ligand of the human orphan G protein-coupled receptor APJ; reported to act as a coreceptor of CD4 for human and simian immunodeficiency viruses. Apelin-17 and apelin-13 represent the predominant molecular forms of apelin present in the whole brain; hypothalamus; and plasma. Like apelin-13; apelin-17 exhibited a high activity on extracellular acidification rate and strongly inhibited forskolin-stimulated cAMP production in CHO cells expressing the human or the rat apelin receptor. The peptide might play a crucial role in the maintenance of body fluid homeostasis by counteracting AVP (arginine vasopressin) actions through inhibition of AVP neuron activity and AVP release.
Storage Shipped at 4°C. Store at -20°C for one year.
Peptide to [Phe17]-Apelin 17
CAS Number: 217082-57-0
Molecular Formula: C96H156N34O20S
Chemical Structure: Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
Lyophilized powder
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